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The RCT is dead. Long live the RCT
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Tufts University School of Medicine Office of Continuing Education

136 Harrison Ave
Boston, MA 02111

2018-2019 Archived Medical Grand Rounds
The RCT is dead. Long live the RCT

Derek C. Angus, MD, MPH, FRCP

Distinguished Professor and Mitchell P. Fink Endowed Chair 

Department of Critical Care Medicine 

University of Pittsburgh and UPMC Health System 

Associate editor, JAMA 


Jointly provided by Tufts University School of Medicine Office of Continuing Education and
Tufts Medical Center, Department of Medicine

Planning Committee:

Deeb Salem, MD – Course Director

Interim CO-President and Chief Executive Officer

Physician-in-Chief , Tufts Medical Center 
Sheldon M. Wolff, Professor and Chairman
Department of Medicine, Tufts University School of Medicine

Richard Kopelman, MD

Professor, Tufts University School of Medicine


Michael Barza, MD

Professor, Tufts University School of Medicine


Karen Freund, MD, MPH

Professor, Tufts University School of Medicine


Joseph Rencic, MD

Associate Professor, Tufts University School of Medicine


Kari Roberts, MD

Associate Professor, Tufts University School of Medicine

Activity Start and Expiration Date: May 20, 2019 – May 19, 2020
Last Review Date: May 20, 2019
Estimated time to complete this activity: 1 hour
There is no fee for this activity.

Requirements for Successful Completion - To receive CME credit/certificate of completion, participants must:

·          View the content

·          Complete the post-test with a passing grade/score of 100%

·          Complete the activity evaluation

Certificates/statements of credit will be available to print/save immediately upon completion of the evaluation and will also accessible in your eeds account.

There was no commercial support received for this activity.

Target Audience
This activity is designed for physicians, residents/fellows/medical students, and other providers in Internal Medicine and other sub-specialties practicing in inpatient and outpatient settings.

Activity Goal
The goal of this activity is to review the latest developments in medical sub specialties as well as changes in evidence-based medicine, evolving understanding about the pathology/pathophysiology of disease and novel therapeutic interventions - all with a focus on disease states commonly encountered by internists in both in- and outpatient settings.

Learner Objectives – Participants will be able to:

·          Choose appropriate and relevant diagnostic tests and therapeutic interventions for disease state of interest.

·          Evaluate individual and system-level challenges to quality patient care.


This activity is designed to address the following ACGME/ABMS and IOM competencies:
Practice-Based Learning/Improvement, Patient Care and Procedural Skills, Medical/Clinical Knowledge, Provide Patient-Centered Care, and Employ Evidence-Based Practice.

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Tufts University School of Medicine Office of Continuing Education (TUSM OCE) and Tufts Medical Center, Department of Medicine. TUSM OCE is accredited by the ACCME to provide continuing medical education for physicians.

TUSM OCE designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Faculty Disclosures
All faculty including course directors, planning committee members, and others in a position to control the content of an educational activity are required to disclose any relevant financial relationships with an ACCME-defined commercial interest. The ACCME defines a commercial Interest as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. Relevant financial relationships are financial relationships in any amount occurring within the past 12 months that create a conflict of interest. Conflicts of interest resulting from a relevant financial relationship are resolved prior to the activity, during the content review.

Derek Angus, MD - Ferring Pharmaceuticals, Inc - Consulting

Derek Angus, MD - Bristol-Myers Squibb - Consulting

Derek Angus, MD - Bayer AG - Consulting

Derek Angus, MD - Beckman Coulter, Inc - Consulting

Derek Angus, MD - Alung Technologies, Inc – Stockholder


Course Director(s)/Planning Committee and Reviewers and TUSM OCE Staff*:
No relevant financial relationships to report in the last 12 months with a commercial interest.

*TUSM OCE Staff: Karin Pearson, CHCP, Mirosleidy Tejeda, MS, Jennifer Besaw, Karlee Pedemonti, MS

ADA/OEO Nondiscrimination Policy
Tufts University School of Medicine (TUSM) considers all applicants and activity participants without regard to race, color, national origin, age, religious creed, sex or sexual orientation.  TUSM is an Equal Opportunity Employer. TUSM does not discriminate on the basis of a disability in admissions, access to treatment, or employment in their programs and activities as identified in the American with Disabilities Act. 

TUSM OCE’s Policy on Privacy and Confidentiality
Please see:

CME Questions
Please contact TUSM OCE at [email protected] or 617-636-6579.

Technical Assistance with eeds Account
Please contact eeds directly at Tech Help or call 828-252-0233.

Complete Enduring Material